People with Down's syndrome can be distinguished on the basis of cholinergic dysfunction.

نویسندگان

  • B Sacks
  • S Smith
چکیده

The mydriatic response to eyedrops of the anticholinergic agent tropicamide at very low concentration (0.01%) has been studied in people with Down's syndrome. By comparison with healthy subjects people with Down's syndrome had responses approximately three times greater, suggesting a peripheral imbalance between cholinergic and adrenergic autonomic influences.

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عنوان ژورنال:
  • Journal of neurology, neurosurgery, and psychiatry

دوره 52 11  شماره 

صفحات  -

تاریخ انتشار 1989